General Health

Leukeran (Chlorambucil)

Leukeran is used for treating certain cancers. It may also be used to treat other conditions as determined by your doctor. Leukeran is an alkylating agent. It works by binding to the RNA or DNA of certain cancer cells, which helps to slow down their growth and reproduction.

This is a potent medication. Take it exactly as prescribed. Unless your doctor instructs you otherwise, drink plenty of fluids while taking this medication. This helps your kidneys to remove the drug from your body and avoid some of the side effects. Do not stop taking this medication, even if you feel nauseated or experience vomiting. If you vomit shortly after a dose, or if you miss a dose, contact your doctor.

Chlorambucil is one of a drugs group, known as alkylating agents; these drugs are also known as cancer drugs, chemotherapy, antineoplastics, or "chemo". They are used in the treatment of various cancers to slow or stop the growth of cancer cells. A combination of different types of cancer drugs will often be used to achieve better results and minimize side effects.

Do not double dose if missed. Contact your doctor.

Store in refrigerator (2 to 8 degrees C) 36 to 46 degrees F.

Leukeran can cause cancer or weaken your bone marrow. Bone marrow is where blood cells are made to protect you against infections/illness. Notify your doctor immediately if you develop signs of infection (persistent sore throat or fever), easy bruising or bleeding, or unusual fatigue. Leukeran may damage chromosomes (genes); has left men and women sterile (inability to have children); and has caused birth defects.